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Experimental HIV Drugs

HIV Drug Development News from IAS 2011 [VIDEO]

Cal Cohen from the Community Research Institute of New England summarizes reports about experimental antiretroviral agents -- and new strategies for using existing drugs -- presented at the 6th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention this week in Rome. alt

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IAS 2011: Once-daily Elvitegravir Matches Twice-daily Raltegravir

The experimental HIV integrase inhibitor elvitegravir works as well as raltegravir (Isentress) for treatment-experienced people with extensive drug resistance, and was well-tolerated overall, according to data presented at the International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2011) this week in Rome. alt

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Tobira Starts Phase 2b Cenicriviroc Trial

Tobira Therapeutics recently opened a middle-phase trial of its dual CCR5/CCR2 inhibitor cenicriviroc (TBR-652).

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Gilead and Tibotec To Develop New Combo Pill

Gilead Sciences and Tibotec Pharmaceuticals announced a collaboration to develop a fixed-dose combination pill containing the protease inhibitor darunavir (Prezista) plus the novel boosting agent cobicistat.

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TBR-652 Inhibits HIV, May Dampen Inflammation

TBR-652, a drug that blocks both CCR5 and CCR2 cell receptors, showed potent antiviral activity against HIV, but did not change most inflammation biomarkers.

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