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Experimental HIV Drugs

ICAAC 2012: New Long-acting HIV Fusion Inhibitor Albuvirtide Looks Promising in Early Studies

A new fusion inhibitor that prevents HIV entry into cells showed potent antiviral activity in early clinical studies and has a long half-life suggesting it may be suitable for once-weekly dosing, Chinese researchers reported yesterday at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) in San Francisco. alt

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Coverage of the 2012 Interscience Conference on Antimicrobial Agents and Chemotherapy

HIVandHepatitis.com coverage of the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), San Francisco, September 9-12, 2012.

Topics highlighted this year include experimental antiretroviral drugs, complications related to HIV and its treatment, recent developments in hepatitis C therapy, cancer caused by HPV, influenza, tuberculosis, and STDs.

Full listing by topic

HIVandHepatitis.com ICAAC 2012 conference section

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HIV Attachment Inhibitor BMS-663068 Looks Good in Early Studies

Bristol-Myers Squibb's novel attachment inhibitor pro-drug BMS-663068, which binds to HIV's gp120 envelope protein, potently suppressed viral load and was generally well-tolerated in a week-long monotherapy study, according to a report in the August 14, 2012, advance online edition of the Journal of Infectious Diseases. A related study showed that the active form of the drug worked against virus resistant to other entry inhibitors. alt

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Coverage of 2012 Interscience Conference on Antimicrobial Agents and Chemotherapy

HIVandHepatitis.com coverage of the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy -- better known as ICAAC -- in San Francisco, September 9-12, 2012.

Topics highlighted this year include experimental antiretroviral drugs, complications related to HIV and its treatment, recent developments in hepatitis C therapy, and cancer caused by HPV, along with a gamut of other infectious diseases including influenza, tuberculosis, and STDs.

Full listing by topic

HIVandHepatitis.com ICAAC 2012 conference section

9/11/12

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FDA Approves Stribild, Gilead's 4-in-1 Quad Pill for First-line HIV Treatment

On August 27, 2012, the U.S. Food and Drug Administration (FDA) approved Stribild, a new single-tablet regimen containing the next-generation integrase inhibitor elvitegravir, the novel boosting agent cobicistat, and tenofovir/emtricitabine (the drugs in Truvada). Stribild is indicated for HIV positive adults starting treatment for the first time.alt

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