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HIV Populations

HIV Infection Can Cause Faster Aging of T-cells

Chronic HIV infection appears to speed up aging of CD4 T-cells by as much as 20-30 years, according to research published online January 26 in the open access journal PLoS ONE. Compared with HIV negative individuals, HIV positive people had shortened telomeres at the ends of T-cell chromosomes, which leads to poor function and cell death. Immune system aging may help explain the higher rates of chronic age-related conditions such as cardiovascular disease seen among people with HIV.

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Tuberculosis Coinfection Increases Risk of Mother-to-Child HIV Transmission

HIV positive women coinfected with tuberculosis (TB) are more likely to transmit HIV to their babies during pregnancy, according to a study described in the February 1, 2011, Journal of Infectious Diseases. These findings underline the importance of TB treatment and use of antiretroviral therapy (ART) to prevent HIV transmission.

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An AIDS-free Generation Is Possible, Says UN Report

Use of antiretroviral drugs has dramatically reduced the rate of mother-to-child HIV transmission worldwide, yet there is still room for improvement according to a report by UN agencies released to coincide with World AIDS Day. In 2009, about half of HIV positive pregnant women received prophylactic antiretrovirals, and an estimated 370,000 babies were born with HIV, mostly in Africa. But perinantal transmission could be eliminated, the report concluded, by expanding access to antiretroviral therapy, especially for the most disadvantage groups including young, poor, and rural women.

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Longer Preventive Therapy, More Drugs Reduce Risk of Mother-to-Child HIV Transmission

Infants born to HIV positive women diagnosed at the time of labor were less than half as likely to be infected if they received 2 or 3 antiretroviral drugs rather than zidovudine (Retrovir; AZT) alone, according to a multinational study presented at the 18th Conference on Retroviruses and Opportunistic Infections (CROI 2011) this month in Boston. A related trial showed that treating infants with nevirapine (Viramune) for 6 months rather than 6 weeks significantly reduced the risk of HIV transmission through breastfeeding.

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Most Gay and Bisexual Men Worldwide Lack Access to HIV Prevention Services

A majority of men who have sex with men (MSM) worldwide do not have access to HIV prevention services including testing, counseling, and free condoms and lubricant, according to an international online survey conducted by the Global Forum on MSM & HIV. In addition to inadequate funding, the organization said stigma, discrimination, and homophobia in many regions discourage gay and bisexual men from accessing the services they need to remain HIV negative.

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