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Large Meta-analysis Shows HIV Positive Women Respond as Well as Men to Antiretroviral Therapy

Treatment-naive and treatment-experienced women with HIV achieve antiretroviral therapy (ART) outcomes similar to those of men, according to a meta-analysis of more than 40 randomized clinical trials presented at the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2010) last month in Boston. Efficacy of all antiretroviral classes was similar for women and men, but women were less likely to prematurely stop study drugs due to treatment failure.

September 18 Is National HIV/AIDS and Aging Awareness Day

Saturday, September 18, is the 3rd annual National HIV/AIDS and Aging Awareness Day, started to call attention to the issues of HIV and AIDS among older individuals. Estimates indicate that by 2015, half of all people living with HIV in the U.S. will be above age 50. People who contracted HIV early in the epidemic are now facing the combined challenges of normal aging plus the effects of living with the virus for decades. At the same time, people age 50 and older continue to become newly infected and may not receive timely care due to the assumption that they are not at risk.

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Promising Long-term Outcomes for Adolescents with Perinatal HIV Infection

Adolescents in France who acquired HIV through mother-to-child transmission during gestation or birth demonstrated relatively good outcomes, especially considering that optimal antiretroviral therapy (ART) was not yet available during their early years, researchers reported in the July 15, 2010 issue of Clinical Infectious Diseases.

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Vitamin Supplements May Increase Amount of HIV in Breast Milk and Raise Risk of Breast Infection

Use of certain vitamin supplements may increase the risk of mother-to-child HIV transmission during breast-feeding, according to 2 recently published studies. One study found that viral load in breast milk increased when women took vitamin A and beta-carotene, while the other found that a multi-vitamin supplement was associated with a greater likelihood of mastitis, or breast inflammation.

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Half of Children Born to HIV Positive Mothers Do Not Receive Preventive Antiretroviral Drugs

Only about half of babies born to HIV positive mothers in 4 African countries received at least a minimum preventive dose of nevirapine (Viramune) immediately after birth to reduce the risk of mother-to-child transmission, according to a study in the July 21, 2010 Journal of the American Medical Association, a special HIV/AIDS issue coinciding with the XVIII International AIDS Conference (AIDS 2010) last month in Vienna. The World Health Organization (WHO) has released new guidelines recommending that all women with HIV should receive antiretroviral drugs to protect against HIV transmission during pregnancy, delivery, or breastfeeding, and that diagnostic testing should be expanded for infants to enable those infected to receive prompt treatment.

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