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Experimental HCV Drugs

EASL 2011: Monoclonal Antibody Bavituximab Well-Tolerated by HIV/HCV Coinfected People

An experimental monoclonal antibody that inhibits HCV replication was safe and well-tolerated in a clinical trial of HIV positive people coinfected with chronic hepatitis C, researchers reported at EASL 2011.

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EASL 2011: Pegylated Interferon Lambda Boosts Response with Few Side Effects

Hepatitis C patients taking an experimental interferon formulation -- pegylated interferon lambda -- had higher rates of rapid and early virological response, with fewer flu-like symptoms and blood cell deficiencies, according to a report at EASL 2011.

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EASL 2011: BMS-790052 + Pegylated Interferon/Ribavirin Works Well for First HCV Treatment

About 90% of treatment-naive genotype 1 hepatitis C patients achieved sustained response at 12 weeks post-treatment using the experimental HCV protease inhibitor BMS-790052 plus pegylated interferon/ribavirin, researchers reported at EASL 2011. alt

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EASL 2011: Once-Daily BI 201335 Ups Response to Interferon for Hepatitis C

Boerhinger Ingelheim's experimental HCV protease inhibitor BI 201335 added to pegylated interferon and ribavirin improved sustained response rates for both treatment-naive and treatment-experienced genotype 1 patients, researchers reported at EASL 2011. alt

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EASL 2011: BMS-790052/BMS-650032 Combo Cures Hepatitis C without Interferon

Most prior non-responders with HCV genotype 1 achieved sustained response with a quadruple combination containing 2 experimental agents plus pegylated interferon/ribavirin, and nearly 40% did so using only the 2 oral drugs -- BMS-790052 and BMS-650032 -- researchers reported at EASL 2011. 

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