Back HIV Prevention Pre-exposure (PrEP)

Pre-exposure Prophylaxis (PrEP)

Preparing for PrEP

PrEP (pre-exposure prophylaxis) is a new HIV prevention tool with great possibilities. Matt Sharp, who served as a community representative on the FDA panel that recommended approval of Truvada (tenofovir/emtricitabine) for PrEP, describes the vote and its implications.alt

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FDA Advisory Committee Recommends Truvada for Prevention of HIV Sexual Transmission

On May 10, 2012, the Antiviral Drugs Advisory Committee of the U.S. Food and Drug Administration (FDA) decisively recommended approval of Truvada -- Gilead Sciences' tenofovir/emtricitabine combination pill -- for pre-exposure prophylaxis (PrEP) to prevent sexual transmission of HIV.alt

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CROI 2012: Drug Levels Predict Efficacy in PrEP Trials, Highlighting Importance of Adherence

Two analyses of PrEP studies presented at the 19th Conference on Retroviruses and Opportunistic Infections (CROI 2012) this week in Seattle found that drug levels -- and by implication, adherence -- were strongly correlated with protection against HIV infection.

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FDA Committee Will Consider Approval of Truvada for HIV PrEP this Thursday

On May 10, 2012, the Antiviral Drugs Advisory Committee of the U.S. Food and Drug Administration (FDA) will hear evidence regarding the use of the tenofovir/emtricitabine combination pill Truvada for pre-exposure prophylaxis (PrEP) to prevent HIV infection. Gilead Sciences requested approval of the expanded indication in December 2011.alt

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CROI 2012: Final Partners PrEP Results Confirm Efficacy of Oral Antiretrovirals for HIV Prevention

Daily, oral pre-exposure prophylaxis (PrEP) using either tenofovir (Viread) or tenofovir/emtricitabine (Truvada) was highly effective at preventing HIV infection in a large study of serodiscordant heterosexual couples in sub-Saharan Africa, researchers reported at the 19th Conference on Retroviruses and Opportunistic Infections (CROI 2012) this week in Seattle.alt

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